Plasmacytoma dog

In the preparation shown here a biopsy taken from the skin of a seven-year-old Golden Retriever, many plasma cells can be seen. We also see anisocytosis and anisokaryosis. The coarse chromatin in the nucleus indicates that something may be wrong. Plasma cells are part of the immune system and are usually found in lymphatic tissue and mucosal surfaces. Plasma cells are immunoglobulin-producing cells that originate from B lymphocytes and are characterized in particular by a large amount of cytoplasm, an eccentrically located nucleus and a perinuclear optically empty court.