Wednesday 28 June 2023

30-year-old female patient. Cervicovaginal cytology.

Cohesive and discohesive groups of superficial and intermediate cells are observed. The presence of mottled cytoplasms many of them with geographic inclusions that acquire a brownish-golden hue is striking. 

© Image by: Dr. Torres Gómez, Francisco Javier

© Image by: Dr. Torres Gómez, Francisco Javier

In such cases, before thinking of infrequent entities with which to explain the morphological and staining phenomenon, the simplest option should be considered. These are glycogen accumulations, more frequent in intermediate cells and in the second half of the cycle.

Generally, large numbers of lactobacilli are found around such clusters waiting for "lunch time" (cytolysis).

📸 Images: Pap stains. 400x / 🔬 Motic Panthera DL
© Dr. Torres Gómez, Francisco Javier
Pathology Service. Virgen Macarena Hospital. Seville. Spain.

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